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Recherche et essais cliniques

En plus du corpus existant de recherches sur le cerveau, l'équipe scientifique de HAPPYneuron Pro, en partenariat avec de prestigieux instituts de recherche, a étudié l'efficacité des exercices sur de multiples pathologies. La recherche et les études cliniques ont montré l'efficacité des exercices, modules et programmes dans l'amélioration des symptômes cognitifs dans de nombreuses pathologies. Voici quelques exemples d'études ci-dessous.

Etudes en lien avec :
Etude
2016-2018: Translational Neuroscience Optimization of GlyT1 Inhibitor
Taille
80 sujets
Institution
Yale University
Chercheurs
John H. Krystal, M.D.
Statut
En cours
Etude
2016-2017: Exploring cognitive training as a non-pharmaceutical therapeutic intervention for people with Huntington's disease
Taille
8 sujets
Institution
Cardiff University in the Cardiff Huntington’s Disease Research Centre
Chercheurs
Emma Yhnell, Pr Anne Rosser
Statut
En cours
Etude
2016-2017: Neural bases of intrinsic motivation for learning in individuals at clinical high risk (CHR) for psychosis
Taille
12 sujets
Institution
Olin Neuropsychiatry Research Center, the Institute of Living at Hartford Hospital
Chercheurs
Jimmy Choi, Godfrey Pearlson, Michael Stevensn Joanna M. Fiszdon
Statut
En cours
Etude
2016-2017: Cognitive training program on verbal memory in older women who are within a year of having undergone chemotherapy treatment for early‐stage breast cancer
Taille
40 sujets
Institution
Rehabilitation Institute of Chicago, Northwestern Feinberg School of Medicine
Chercheurs
Leora R. Cherney, Diane F. Morean, Alyx Kesselring
Statut
En cours
Etude
2016: CBT for psychosis in combination with Cognitive Remediation
Taille
40 sujets
Institution
Addictions & Mental Health Services - Kingston Frontenac Lennox & Addington
Chercheurs
Dr. Farooq Naeem, Dr. Tariq Munshi, Dr. Muhammad Ayub, Dr. Rupy Johal
Statut
En cours
Etude
2016: Evaluation of cognitive tele-rehabilitation program for children with Attention Deficit Hyperactivity Disorder
Taille
100 sujets
Institution
Bio functional Studies Institute - Universidad Complutense (Madrid)
Chercheurs
Elimelech Duarte, Jesus Alvarado, Alejandra Koeneke
Statut
En cours
Etude
2015-2018: Cognitive and Physical Training in Elderly: Behavioral and EEG study
Taille
120 sujets
Institution
Laboratoire d'Etude des Mécanismes Cognitifs, Université Lumière Lyon 2, France
Chercheurs
Clémence Joubert (Ph.D student) & Hanna Chainay, Ph.D.
Statut
En cours
Etude
2015-2017: Evaluation of Dallas Metrocare's Enhanced Program for Early Psychosis (ePEP)
Taille
90 sujets
Institution
UT Southwestern Medical Center
Chercheurs
Carol North, Ana Stan, Debra Bushong, Draper Bushanan
Statut
En cours
Etude
2015-2016: Measuring the effectiveness of Cognitive Remediation on Schizophrenia and Depression
Institution
National Center of Neurology and Psychiatry, Japan
Chercheurs
Kazuyuki Nakagome, M.D., Ph.D.
Statut
En cours
Etude
2014-2019: Effectiveness of metacognitive training (MCT) and cognitive remediation (CR) at treating the persistent symptoms and functional deficits present in those with schizophrenia.
Taille
75 sujets
Institution
University of British Columbia
Chercheurs
Todd Woodward, Ph.D.
Statut
En cours
Etude
2014-2018: Manualized group cognitive-behavioral therapy for social anxiety in first episode psychosis: A randomized controlled trial
Taille
120 sujets
Institution
Douglas Mental Health University Insitute, Montreal, QC & Department of Psychiatry, McGill University, Montréal QC
Chercheurs
Dr Martin Lepage, Ashol K. Malla, Dr Philippe-Olivier Harvey, Dr. Christopher Bowie
Statut
En cours
Etude
2014-2018: Effectiveness of metacognitive training (MCT) and cognitive remediation (CR) at treating the persistent symptoms and functional deficits present in those with schizophrenia.
Taille
75 sujets
Institution
University of British Columbia
Chercheurs
Todd Woodward, Mahesh Menon, Devon Andersen
Statut
En cours
Etude
2014-2017: The FOCUS trial: cognitive remediation plus standard treatment versus standard treatment for patients at ultra-high risk for psychosis: study protocol for a randomised controlled trial
Taille
126 sujets
Institution
Psychiatric Center Copenhagen, Denmark
Chercheurs
Louise B Glenthøj, Birgitte Fagerlund, Lasse Randers, Carsten R Hjorthøj, Christina Wenneberg, Kristine Krakauer, Astrid Vosgerau, Christian Gluud, Alice Medalia, David L Roberts, Merete Nordentoft.
Statut
En cours
Etude
2014-2016: Cognitive Training protocols in people with Chronic Pain
Taille
50 sujets
Institution
School of Psychological Sciences, Monash University; and Caufiled Pain Management and Research Center, Caulfield Hospital
Chercheurs
Dr. Melita Giummarra, Pr. Nellie Georgiou-Karistianis, Pr. Stephen Gibson, Katharine Baker
Statut
En cours
Etude
2014-2016: Comparing interventions that have either been designed to target the positive symptoms (particularly delusions) or the cognitive symptoms (e.g., memory and language deficits) of Schizophrenia
Institution
School of Psychology, Flinders University, Adelaide, SA, Australia
Chercheurs
Dr Ryan Balzan
Statut
En cours
Etude
2014-2015: Preparing people marginalized by mental health issues for further education/ employment through Education
Taille
25 sujets
Institution
George Brown College
Chercheurs
Jaswant Kaur Bajwa, Alex Irwin
Statut
En cours
Etude
2014: Increased activation in Broca's area after cognitive remediation in schizophrenia
Taille
16 sujets
Institution
Lausanne Hospital, Switzerland
Chercheurs
Pascal Vianin, Ph.D., Sébastien Urben, Pierre Magistretti, Pierre Marquet, Eleonora Fornari, Laure Jaugey
Statut
Terminée
Publication
Pascal Vianin, Sébastien Urben, Pierre Magistretti, Pierre Marquet, Eleonora Fornari, Laure Jaugey. Increased activation in Broca's area after cognitive remediation in schizophrenia. Psychiatry Research: Neuroimaging, Volume 221. Issue 3, 30 March 2014, pp 204-209. Click Here to Get an Electronic Copy
Etude
2014: Remote Cognitive Remediation for Psychosis
Statut
En cours
Etude
2014: Cognitive Remediation for Geriatric Schizophrenia
Statut
En cours
Etude
2014: Short-term, Intensive Executive Functioning Training with an Active Placebo
Statut
En cours
Etude
2014: Remote Cognitive Remediation for Acutely Hospitalized Depression
Statut
En cours
Etude
2014: Cognitive training to improve language comprehension for seniors?
Taille
50 sujets - under recruitment
Institution
Jean-Uhrmacher Institut für klinische HNO-Forschung, Klinik und Poliklinik für Neurologie der Uniklinik Köln, Lehrstuhl für Pädagogik und Didaktik hörgeschädigter Menschen
Chercheurs
Dr. Magdalene Ortmann, Prof. Dr. Harmut Meister, Prof. Dr. Josef Kessler, Prof. Dr. Thomas Kaul
Statut
En cours
Etude
2013-2016: Web-based cognitive training for breast cancer survivors with cognitive complaints—a randomized controlled trial
Taille
157 sujets
Institution
Unit for Psychooncology and Health Psychology, Department of Oncology, Aarhus University Hospital and Department of Psychology and Behavioural Science, Aarhus University, Denmark
Chercheurs
MF Damholdt, M Mehlsen, MS O’Toole, RK Andreasen, AD Pedersen, R Zachariae.
Subventionné par
Research was supported by TrygFonden
Statut
Terminée
Etude
2013-2015: Efficacy of psychological treatments for schizophrenia
Institution
School of Psychology, Flinders University, Adelaide, SA, Australia
Chercheurs
Dr Ryan Balzan
Statut
En cours
Etude
2013-2015: Scanning Training Rehabilitation for Visual Field Loss after stroke at Home: The STaRFiSH Study
Institution
Glasgow Caledonian University
Chercheurs
Christine Hazelton, Dr. Alex Pollock
Statut
En cours
Etude
2013-2015: Effects and efficacy of specialized social cognitive therapy compared to cognitive remediation therapy in people with schizophrenia
Taille
30 à 40 sujets
Institution
McGill University Psychiatry Department
Chercheurs
Philippe-Olivier Harvey
Statut
En cours
Etude
2013-2014: Cognitive remediation for neuropsychological impairment in hoarding disorder: A pilot study
Taille
17 sujets
Institution
University of British Columbia
Chercheurs
Jennifer DiMauro
Statut
Terminée
Publication
Jennifer DiMauro, Marla Genova, David F. Tolin, Matthew M. Kurtz, Cognitive remediation for neuropsychological impairment in hoarding disorder: A pilot study, Journal of Obsessive-Compulsive and Related Disorders, Available online 2 April 2014, ISSN 2211-3649.
Etude
2012-2015: Identifying neuropsychological subgroups in patients with bipolar disorder and evaluation of a cognitive remediation program
Taille
190 sujets
Chercheurs
Statut
En cours
Etude
2012: Conditions for Maximizing Effects of 90 Days of Brain Training
Taille
350 sujets
Statut
Terminée
Etude
2011-2013: Neurocognitive Enhancement in a Vocational Services Program
Taille
60 sujets
Statut
En cours
Etude
2011-2013: Cognitive Remediation for Treatment Resistant Depression
Statut
Terminée
Publication
Bowie CR, Gupta M, Holshausen K, Jokic R, Best, M, Milev, R. Cognitive remediation for treatment resistant depression: Effects on cognition and functioning and the role of online homework. Journal of Nervous and Mental Disorders, 2013, 201, 680-685.
Etude
2011: Increased employability of the unemployed aged 50+ through cognitive training?
Taille
87 sujets
Chercheurs
B. Godde, C. M. G. Noack, C. Windisch & C. Voelcker-Rehage
Statut
Terminée
Etude
2010-2011: Cognitive Remediation Early Episode vs. Chronic Outpatients with Schizophrenia
Taille
30 sujets
Subventionné par
NARSAD
Statut
Terminée
Présentation
Publication
Bowie CR, McGurk SM, Mausbach BT, Patterson TL, Harvey PD. Combined cognitive remediation and functional skills training for schizophrenia: effects on cognition, functional competence, and real world behavior. American Journal of Psychiatry, 2012, 1-9
Etude
2009-2011: Intensive Spatial Memory Training for older Adults
Taille
40 sujets
Chercheurs
Statut
Terminée
Publication
Pending
Etude
2009-2011: Neurocognitive Enhancement Therapy for Major Depressive Disorder
Taille
40 sujets
Statut
Terminée
Présentation
Publication
Pending
Etude
2009: Specificity and Generalizability of Cognitive Remediation and Functional Skills Training in Schizophrenia
Taille
83 sujets
Subventionné par
NARSAD
Statut
Terminée
Présentation
Publication
Pending
Etude
2008-2012: Cognitive rehabilitation for depressed patients
Taille
30 sujets
Institution
French National Science Research Center
Paris 6 University at La Pitié-Salpêtriére Hospital
Statut
Terminée
Publication
Pending
Etude
2008-2011: Cognitive remediation effectiveness for schizophrenic patients
Taille
280 sujets multi-site
Chercheurs
Nicolas Franck, Institute for Cognitive Science, Lyon, France
Subventionné par
Funded by PHRC (French Government Funding Program for Clinical Research)
Statut
Terminée
Présentation
Publication
Franck, N. et al. (2013). Specific vs general cognitive remediation for schizophrenia: a multicentre randomised trial. Schizophrenia Research, 147(1), pp. 68-74. Click Here to Get an Electronic Copy
Etude
2008: Cognitive Training Improves Driving Skills
Taille
90 sujets
Statut
Terminée
Résultats
Subjects demonstrate an average of 14% improvement in key skills
Etude
2008: Benefits of Online Cognitive Training
Taille
217 sujets
Statut
Terminée
Résultats
Subjects demonstrate +8.5% average improvement
Publication
Pending
Etude
2007: Alzheimer's patients maintain cognitive skills and improve self confidence
Taille
47 sujets
Chercheurs
Dr. Foare, Sophia's Gardens, Alzheimer's disease clinic, Castelnau-le-Lez, France
Statut
Terminée
Etude
2007: Online Cognitive Training Improves Cognitive Performance
Taille
85 sujets
Statut
Terminée
Résultats
85 HAPPYneuron Users show +16% average improvement in 18 weeks
Etude
2007: Significant Brain Activity Improvement
Chercheurs
Subventionné par
The Center for Disease Control (CDC)
Statut
Terminée
Résultats
“Shows Significant Brain Activity Improvement. HAPPYneuron™ Games Key Component of Brain Wellness Program”
Etude
2006-2008: Rehabilitation software program for schizophrenia patients
Taille
28 sujets
Institution
Lausanne Hospital, Switzerland
Subventionné par
CHUV (Centre Hospitalier Universitaire Vaudois)
Statut
Terminée
Publication
Vianin, P., Deppen, P., Croisile, B., Tarpin-Bernard, F., Sarrasin-Bruchez, P., Dukes, R., Grillon, M. Exploratory Investigation of a Customized cognitive remediation program for individuals living with schizophrenia. The Journal of Cognitive Rehabilitation, NeuroScience Publishers, Volume 28. Fall 2010, pp 11-21, Click Here to Get an Electronic Copy
Etude
2006: Memory Stimulation. Which scientific benefits? Which exercises?
Taille
39 sujets
Statut
Terminée
Résultats
HAPPYneuron Users show +12% average improvement in 18 weeks
Etude
2004-2006: MNESIS Project - Using the internet as a means of social integration and cognitive stimulation in a residential unit for elderlies
Institution
Lyon 2 University, Lyon INSA (ICTT), Medica-France
Chercheurs
Michel C., Bobillier-Chaumon M.-E., Cohen-Montandreau V., Tarpin-Bernard F.
Subventionné par
French Ministry of Industry
Statut
Terminée
Présentation
Elderlies in residential home care units. Can ICT be considered as a social rebinding method? In Conférence EUTIC 2006
Publication
Marc-Eric Bobillier Chaumon, Christine Michel, Franck Tarpin Bernard & Bernard Croisile , Behaviour & Information Technology (2013): Can ICT improve the quality of life of elderly adults living in residential home care units? From actual impacts to hidden artefacts, Behaviour & Information Technology, pp 1-17. Click Here to Get an Electronic Copy
Etude
2003-2006: The Importance of Memory and Concentration Skills for Schoolchildren
Taille
130 sujets school children ages 10 and 11, over a 3 year time frame
Institution
City of Elancourt, France ; Association Initiatives Terrain, France ; Lille University, France
Chercheurs
Neukirch A., Fenouillet F., Hildebrandt R.
Statut
Terminée
Résultats
Better CMS score and various effects on recognition tasks.
Publication
Pending
Etude
2001-2002: Transferability of Cognitive Training to every-day activities (AKA King 64)
Taille
117 sujets children, 10 years old
Institution
EMC laboratory (Université Lyon II - CNRS), France
Chercheurs
Statut
Terminée
Résultats
Average of 40%+ improvements in various cognitive skills performance.